The type of question you need to answer can help you determine what type of study to look for (presented in order of preference):
| ALL CLINICAL QUESTIONS
ETIOLOGY OR HARM (CAUSATION)
PROGNOSIS (NATURAL HISTORY)
See the Study Definitions tab for more about each study type. See the box below for search techniques to find different types of evidence.
NOTE: PubMed is currently updating the appearance of its website, so some of the screenshots below may look different than what you see.
Note: In the Cochrane Library database, selecting a suggested term from the drop-down menu puts the term inside double quotation marks, which means variations of the term will not be searched. To catch alternate spellings, plurals, etc., remove the quotation marks before running your search.
Sometimes, despite your best efforts, you find few or no articles related to your clinical question. Not every PICO(T) has a perfect article, so you may need to make a decision as to what matters most to your research. If you are unable to find evidence, here are some strategies: